The Clinical Challenge
- Lack of Reliable Prediction MethodsPredicting outcomes and recurrence risk after oral cancer treatment remains a significant challenge. Current pathological information (LVI, ENE, or BNI) is informative, but not indicative enough for accurate recurrence prediction.
- Shortage of pathologists and limited resourcesThe critical shortage of trained pathologists, especially in resource-limited settings, delays diagnosis and treatment initiation when timely intervention matters most.
- Variability in Pathological AssessmentDifferent pathologists often reach different diagnostic conclusions on the same tissue sample. This interobserver variation can lead to missed early signs of malignancy and delayed treatment initiation.